Sebaceous hyperplasia is a common, benign condition of sebaceous glands in adults of middleage or older.
Lesions can be single or multiple and manifest as yellowish, soft, small papules on the face (particularly nose, cheeks, and forehead). Sebaceous hyperplasia occasionally also occurs on the chest, areola, mouth, and vulva.
Sebaceous hyperplasia is the most common of all pilosebaceous tumours. It is a disproportionate enlargement of the sebaceous glands found most commonly on the foreheads and cheeks of middle-aged to older individuals. These areas of hyperplasia consist of one or more lesions size 2 to 4 mm in diameter with umbilicated papules that most commonly have a yellowish hue. Pathologically, there is an increased number of mature sebocytes aggregated into large nodules that cluster around a central duct. This is commonly viewed as a central umbilication. The sebaceous lobules show proper maturation with only a single rim of basaloid cells at the periphery and the mature sebocytes within this central portion of the lobules. Sebaceous hyperplasia must be distinguished from basal cell carcinoma. Usually this can be determined clinically; however, in close cases, a biopsy may be warranted. Oftentimes the yellowish coloration and the central umbilification are key points in suggesting that it is indeed sebaceous hyperplasia.
Oral isotretinoin or Roaccutane has proven effective in clearing some lesions after 2-6 weeks of treatment, but lesions often recur upon discontinuation of therapy; maintenance doses of oral isotretinoin in the range of 10-40 mg every other day or 0.05% isotretinoin gel is rarely indicated as a suppressive treatment for widespread disfiguring sebaceous hyperplasia.
In Office Treatments:
For more permanent results treatment of sebaceous gland hyperplasia at Skin Renewal includes as in-office combinations of Cryotherapy, Photodynamic therapy with a light sensitiser such as ALA and medium depth chemical peel such as Mela M and TCA and to improve the appearance of sebaceous hyperplasia.
Often a biopsy will provide diagnostic material as well as remove the lesion. As each patient's case is different; we will tailor a treatment program specifically for you and your circumstances. A highly professional team led by a medical doctor assesses every patient and an appropriate combination treatment together with long term maintenance program is recommended.
Skin Renewal Tip
Photodynamic therapy PDT done after a light sensitizer such as ALA will shrink the pilosebaceous unit causing the sebaceous hyperplasia, provide more permanent results and provide skin rejuvenating benefits as well. In addition, any possible skin cancers are treated at the same time.