Injectable mesotherapy with biostimulatory agents is a state-of-the-art, minimally invasive aesthetic procedure that delivers micro-injections of specialised solutions into the dermal layer of the skin. These solutions blend vitamins, minerals, amino acids, hyaluronic acid, and advanced biostimulatory compounds, such as Calcium hydroxyapatite (CaHA), poly-L-lactic acid (PLLA), or Polycaprolactone (PCL), to initiate the skin’s own regeneration processes.
Key Benefits of Biostimulation
- Stimulates the skin’s natural regenerative processes to support long-term collagen and elastin production.
- Improves skin texture, luminosity, elasticity and firmness.
- Suitable for addressing early to moderate signs of ageing, skin laxity and mild volume loss.
- Provides gradual, natural-looking rejuvenation with minimal downtime and low risk of adverse effects.
How Biostimulation Differs from Traditional Mesotherapy and Dermal Fillers
- Traditional mesotherapy typically injects hydrating and revitalising cocktails (vitamins, amino acids, hyaluronic acid) to refresh the skin, but does not substantially stimulate collagen synthesis.
- Biostimulatory mesotherapy, however, targets the deeper dermal layers and harnesses active compounds (CaHA, PLLA, PCL) to drive actual tissue remodelling rather than just superficial improvement.
- Dermal fillers, by contrast, primarily add volume and structural support; biostimulation focuses on encouraging the skin to strengthen itself from within rather than just filling deficits.
Biostimulation vs Biorevitalisation vs Bioremodeling
- Biostimulation: Treatment that activates the body’s own dermal regeneration—especially fibroblast activity, to increase collagen, elastin and hyaluronic acid production. Common active substances: CaHA, PLLA, PCL, sometimes combined with hyaluronic acid. Ideal for improving “inside-out” skin quality, rather than adding volume.
- Biorevitalisation: Non-volumising minimally invasive injection of biologically active compounds (concentrated hyaluronic acid, vitamins, peptides, antioxidants) for deep skin hydration and tone restoration. Focused on revitalising cell metabolism rather than structural change.
- Bioremodeling: High-concentration hyaluronic acids or specialised compounds injected at deeper dermal/subcutaneous layers to remodel the skin’s deeper architecture. Designed for sagging, loss of elasticity and deeper wrinkles, closer to structural lift than mere surface improvement.
Who Is This For?
Individuals who may benefit include those with:
It’s also ideal as a preventive skin rejuvenation strategy for patients seeking subtle, natural results with low downtime. Extensive volume loss or advanced sagging may require bioremodeling or volumising fillers (or both) for optimal results.
Why Choose Skin Renewal
At Skin Renewal, we offer a doctor-led, customised approach to injectable mesotherapy with biostimulators. Each patient receives a thorough skin assessment, a tailored treatment protocol, and a multi-modality strategy combining injections with in-clinic treatments (such as microneedling, lasers, and radiofrequency) to maximise collagen activation and skin rejuvenation.
Our experienced medical aesthetics team ensures safe protocols, premium materials (CaHA, PLLA, PCL) and realistic outcomes aligned with your aesthetic goals, achieving subtle, natural-looking rejuvenation without the appearance of ‘over-done’ filler volume.
