Dermamelan Depigmentation at a Glance

Best Results 1 - 2
Duration of Results 10 - 12 months
Treatment Recovery 7 - 14 days
Risks & Complications Medium
Anaesthetic None
Procedure Time 30 mins
Skin Specialist Doctor
Back To Work Next day - 4 days

Frequently Asked Questions

Dermamelan is available in Johannesburg at FourwaysParkhurstMorningside, BedfordviewWest Rand, Waterfall and Illovo as well as in Pretoria at Brooklyn and Irene and in the Western Cape at Cape QuarterClaremontConstantiaStellenboschWillowbridgePaarl, and in KwaZulu-Natal at BallitoDurban & Umhlanga.

Skin ageing caused by systematic sun exposure, facial blemishes due to excessive pigmentation and, in general, imperfections caused by melanin, are more and more common problems today. “Dark blemishes”, especially on hands and face, are one of the greatest aesthetic concerns of modern men and women… It will only be possible to remove the anti-aesthetic skin blemishes and recover the smoothness of the skin, bringing back its luminosity, with a treatment that has a direct effect on the intimate formation process of the pigment (melanin).

At Skin Renewal, to improve results with Dermamelan, a Mesoestetic Melanostop peel is applied immediately before the mask treatment at no extra cost.

Dermamelan has similar active ingredients to Cosmelan but at 20 % higher concentration and the mask treatment and follow up must be done under strict supervision of a cosmetic doctor. Dermamelan treatment guarantees the improvement of skin blemishes with a very high safety margin. Dermamelan Depigmentation treatment’s principal action is the elimination of melanin patches on the face - melasma, also called chloasma if the pigmentation occurs with pregnancy. Dermamelan Depigmentation treatment involves a very versatile, dynamic process which is easily adapted to the needs of each individual patient.

Dermamelan Depigmentation treatment action mechanism is based on the inhibition of tyrosinase, a basic enzyme in the melanin formation process. Several of the substances present in the Dermamelan formula act by blocking this enzyme, or even by inverting the metabolic process of the transformation chain. Melanogenesis comprises the following stages:

  1. TYROSINE proceeds to DOPA by means of TYROSINASE.
  2. DOPA proceeds to DOPAQUINONE by means of TYROSINASE.
  3. DOPAQUINONE proceeds to PHAEOMELANINE and EUMELANIN by means of oxidation and cyclization.

The Dermamelan Depigmentation treatment offers a series of major advantages and benefits compared with other types of depigmentation products found in the market:

  • Very effective in all types of Melasma especially deep-seated severe Melasma or post-inflammatory hyperpigmentation PIH
  • Effective for pigmentation that has failed to resolve after traditional skin lightening products
  • Effective for pigmentation that has failed to resolve after traditional treatments such as superficial peels
  • Rapid and easy depigmenting action
  • Compatible with ALL skin types (Fitzpatrick I – VI)
  • Light peeling effect
  • Rejuvenates the skin
  • Treatment can be used all year round
  • Beneficial for acne patients
  • Does not contain Hydroquinone or TCA
  • High safety margin

In 99% of the cases, the disappearance of the blemishes improves by 95%...

ONE WEEK after starting the Dermamelan Depigmentation treatment, a noticeable significant improvement of the skin is observed! The reduction of the treated blemish is detected and the appearance of new luminous and rejuvenated skin is present. At the end of the Dermamelan Depigmentation treatment, the blemishes start to disappear altogether, so that, although the patient may be able to “locate” the place where the spot was, the truth is that the pigmentation will have disappeared and nobody will be able to see it just by looking at it.

Dermamelan works by blocking the process that causes hyperpigmentation. It works for:

  • Melasma
  • Brown Spots
  • Blotchy Skin
  • Hyperpigmentation post acne spots
  • Post-inflammatory hyperpigmentation
  • Prevention of hyperpigmentation post-laser and post-peel

Dermamelan has similar active ingredients to Cosmelan but at 25 % higher concentration.

Dermamelan 1 – mask
Azelaic Acid, Kojic Acid, Phytic Acid, Ascorbic Acid, Arbutine, and Titanium Dioxide
Dermamelan 2 – Maintenance Cream (30g)
Titanium Dioxide, Kojic Acid, Phytic Acid, Ascorbic Acid
Mesoestetic® Hydra Vital Factor K Cream (50ml)
Hydro nutritional cream for face and neck. Hydroviton, VItamin K, Vitamin E, Amniotic fluid, Glycerine, Silicone oil.

Please inform your cosmetic doctor if you have undergone any previous treatments, especially with glycolic acid. If confirmed, any treatment, especially Glycolic Acid, must be eliminated at least, one week prior to using Dermamelan Depigmentation treatment.

The Dermamelan Depigmentation treatment initiated at the medical office must be continued at home, on a daily basis, according to the guidelines indicated.

The treatment must not be interrupted under any circumstances, during the whole time prescribed.

It is completely forbidden to combine the Dermamelan Depigmentation treatment with other depigmentation treatments, as the appearance of undesired effects cannot be guaranteed.

Treatment control visits are recommended. 8 days after beginning of treatment, 15 days after, and a follow up visit every month thereafter.

First and second day

During the first two days of the treatment, the skin may turn red. If the skin is very sensitive, the patient may experience an itching feeling. Slight burning and tightening of the skin is also absolutely normal, especially during the first 24 to 48 hours after starting the treatment. To relieve these problems, it is advisable to apply the Mesoestetic® Hydra-vital factor K whenever necessary.

Reddening of the Skin that occurs on the face after applying the Mesoestetic® Dermamelan mask treatment; is similar to the effects of day-long exposure to the sun or the snow without sun protection (Intense reddening in skin type I and II and practically non existent in skin type IV and V).

Flaking may occur on all skin types (and more intensely in skin type I and II) between the second and third day. In this case it is advisable to apply the Mesoestetic® Hydra-vital factor K cream, repeating this every two hours on the day when the flaking is most intense repeating this every 2 hours until it improves. Do not pull on the flakes. Do not rub or scratch the skin. If necessary flakes can be cut off. Do not use exfoliants, scrubs or peels. Avoid steam baths, saunas and swimming in a hot spring for 2 weeks following treatment. It is advisable to wait until the initial flaking period is over before starting to apply make-up again.
If a severe skin reaction results from treatment do not proceed with maintenance treatment. Similarly, if scab formation is seen or if the skin is accidentally injured during the treatment period it is advisable to interrupt application of maintenance treatment. Use only Hydra-vital factor K and Sunscreen until the skin has settled and then again proceed with the maintenance treatment schedule. If in doubt, please contact your doctor at Skin Renewal immediately.

Third and fourth day

After the third or fourth day, the skin appears healthy and luminous and the marks begin to fade.

HOME TREATMENT – Dermamelan Maintenance Cream The second phase of the Dermamelan consist of a home maintenance cream Dermamelan with the intention of securing the depigmentation by association of agents such as Kojic Acid, Phytic Acid, and Vitamin C. We have added a physical agent to block the sun and guarantee that the UV rays do not keep on aggravating unwanted skin hyperpigmentation.

When you start using your Dermamelan 2 (active products), please do so in the following manner, known as the 3:2:1 protocol: (Please use sparingly – overuse of the maintenance cream can cause sensitivity)

  • Month 1 (at least four weeks): Apply your product every 3rd night/day (as prescribed).
  • Month 2 (at least four weeks): Apply your product every 2nd night/day (as prescribed).
  • Month 3 (ongoing): Apply your product every night/day (as prescribed).

The period following the initial 6 month treatment process, is called the STABILISATION period, and this can ideally be extended up to one year. Every effort should be made to continue treatment throughout the first summer. Even if the treatment is a great success, long term success depends on how well the protocol is followed, during both the treatment and stabilization phases. VERY GOOD sunblock is essential at all times.

Mesoestetic Vitamin C ampoules: use twice weekly before applying the Cosmelan 2 cream.

Hydra Vital K:The recommended moisturizer.
Regenerance Active:recommended moisturiser for sensitive skin.
Mesoestetic Complete sunblock:Highly recommended for continuous use.
Melanogel Touch:this can be applied on heavy spots. Recommended for added benefit.
Melanogel Touch anti-spot cream:this depigmentation cream works very well to maintain results during stabilization period.

IMPORTANT NOTE: The treatment results are largely dependent on your cooperation and adherence to the post treatment skin care! The first 4 months constitute the treatment period. The period following is called the stabilisation period, and this is ideally extended up to one year, or longer. Every effort should be made to continue treatment throughout the first summer. Even if the depigmentation treatment was a great success, you need to understand that long term success depends on how well the protocol is followed, during both the treatment and stabilization phases. Avoid sun exposure for 2 weeks prior to treatment.

No peels can be done 2 weeks prior to treatment

No Laser treatment can be done on area to be treated 2 days prior to peel
Avoid Injectable treatments in area to be treated 2 weeks prior to peel

5 Reviews (average: 5 out of 5)

See all reviews
*Please note results may vary by individuals.
Review -Thanks Skin Renewal, you guys rock!
Reviewed on 3 July 2015 by Minki Witbooi

I visited Skin Renewal to seek help for my pigmentation. The doctor explained everything step by step. The staff is friendly and kind. I really see improvement on my face. My therapist Melissa is just amazing. I can't wait to see the end results. Thanks Skin Renewal, you guys rock!

Review -Bravo Dr. Maureen!
Reviewed on 2 July 2015 by Marc le Sueur

Thank you, Dr. Maureen, you are like a breath of fresh air. So polite, kind and professional.

Review -People comment on how good my skin looks
Reviewed on 13 April 2015 by Michelle Davias

My battle with severe pigmentation has been for several years - I went to every doctor, dermatologist, plastic surgeon available to me. I have done Fraxel, to name a few, all these treatments would only cause slight improvement and then a month or two later it would come back in some way darker than it originally was. Doctor Allem has been my saving grace. I wish I came to her sooner, she is a power house of knowledge on all issues, specially relating to pigmentation and ageing. People comment on how nice my skin is looking and ask what I have done. I would only recommend Dr Allem and her branches. I cannot express my thanks to her enough.

Review -I am renewed
Reviewed on 30 January 2015 by M.L.B from Skin Renewal Fourways

I used skin brightening with Hydroquinone on my skin, my face had two colours. Thanks to my Dr, for a non-surgical solution. I now have my confidence back, I can go out without wearing any make-up. I am renewed. Thanks to Dr and the staff. You're forever smiling and reminding me of my appointments. Stay blessed.

Review -Very Satisfied
Reviewed on 6 September 2014 by Anonymous

I am very satisfied with the service at the Fourways branch. The doctors and the therapists are professional and competent and the support staff are brilliant. The friendly and professional way you are treated truly is to be commended. Even the one problem i did have was handled so well by the manager and smoothed over effortlessly. Thank you very much to everyone at Fourways!

Sharon Izak Elaine Chat staff ) WhatsApp