Profhilo Injectable Bio-Remodelling | Anti-Ageing

Profhilo®

Ageing gracefully is not about transformation, but restoration, bringing back the softness, radiance, and elasticity that time gradually diminishes. Profhilo embodies this philosophy. As one of the most advanced bioremodelling treatments in aesthetic medicine, it delivers deep hydration and cellular renewal without altering the natural contours of the face. Instead, it enhances what is already yours, reviving the skin’s luminosity, firmness, and vitality from within.

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Profhilo® at a glance

Best Results

2-4 Treatments

Anaesthetic

None

Duration of Results

Up to 6 months

Procedure Time

30-60min

Treatment Recovery

None

Skin Specialist

Doctor

Risks & Complications

Low

Back To Work

Same Day

Profhilo has rapidly become one of the most sought-after injectable treatments in aesthetic medicine, thanks to its ability to deeply hydrate, firm, and rejuvenate the skin, without adding volume or altering facial features. Known for its unique bioremodelling effect, Profhilo delivers both immediate radiance and long-term structural improvement, making it a top choice for patients seeking natural, healthy-looking skin enhancement.

What Is Profhilo?

Profhilo is an award-winning bioremodelling injectable formulated with one of the highest concentrations of pure hyaluronic acid (HA) available in aesthetic medicine. Unlike traditional dermal fillers, which add volume, or typical skin boosters, which deliver hydration only, Profhilo is thermally stabilised rather than chemically cross-linked. This allows it to spread seamlessly beneath the skin and stimulate profound, multi-layered rejuvenation.

Once injected using the BAP (Bio Aesthetic Points) technique, Profhilo diffuses evenly through the tissue, creating a reservoir of deep hydration while triggering the natural production of collagen and elastin. It is most commonly used on the face. Still, it is equally effective for the neck, hands, décolleté, and other areas experiencing skin laxity or dullness.

How Profhilo Works

Profhilo works through a powerful two-phase mechanism that refreshes the skin instantly while improving its quality over time.

How Profhilo Works

Key Benefits of Profhilo

Profhilo offers noticeable, progressive improvement without changing facial structure, making it ideal for those seeking subtle yet meaningful results.

Hydration & Radiance

Deep, long-lasting hydration
Dewy, glowing complexion
Improved moisture retention

Skin Firmness & Elasticity

Stimulates collagen and elastin
Reduces skin laxity
Enhances firmness and density

Texture & Tone Improvement

Smoother, more even skin
Reduction in roughness and crepiness
Healthier, more refined texture

Natural, Non-Volumising Effect

No overfilling or puffiness
Preserves natural facial expressions

Versatility

Suitable for face, neck, hands, décolleté, and body areas prone to laxity

Minimal Downtime

Quick treatment (±30 minutes)
Small injection bumps settle within 12–24 hours

Who Is Profhilo For?

Profhilo is ideal for adults, typically from their 30s onwards, who are noticing early to moderate signs of ageing, such as:

Dull, dehydrated, or lacklustre skin.
Fine lines or early creases.
Mild laxity around the cheeks, jawline, or neck.
Crepey texture on the face, neck, or hands.
General skin quality concerns.

frequently asked
questions

Is Profhilo® available at all Skin Renewal branches?

Profhilo® treatments are available in Gauteng at the Morningside, Parkhurst, Rosebank, Bedfordview, Fourways, West Rand, Irene, Waterfall, Irene, Lynnwood and Brooklyn clinics, as well as in the Western Cape at Cape Quarter, Claremont, Constantia, Century City, Stellenbosch, Paarl and Willowbridge clinics, and Kwa-Zulu Natal at the Ballito, Durban and Umhlanga clinics.

Is Profhilo painful?

Profhilo is generally very well tolerated. Most patients describe the treatment as mildly uncomfortable rather than painful. The injections are placed at five strategic Bio Aesthetic Points on each side of the face, which minimises the number of needle insertions required. A topical numbing cream can be applied beforehand if needed, and any discomfort is brief, resolving within seconds. Most people comfortably resume their routine immediately afterwards.

When can you expect to see results from Profhilo?

You may notice increased hydration and a subtle glow within the first few days. However, the most significant improvements (firmer skin, better elasticity, smoother texture, and reduced crepiness) develop progressively as collagen and elastin production increase. Optimal results usually appear 4–8 weeks after the second session, with peak improvement around weeks 8–10.

How long do Profhilo results last?

Results typically last 6–9 months, depending on factors such as skin quality, age, lifestyle, and metabolic status. To maintain the benefits, most patients schedule a maintenance session every six months. However, some choose quarterly boosters for enhanced, ongoing bioremodelling.

What is the downtime after a Profhilo treatment?

Downtime is minimal. You may notice temporarily raised bumps (similar to small mosquito bites) at the injection sites. These typically flatten within 6–24 hours as Profhilo spreads through the tissue. Mild redness or tenderness can occur but usually resolves within a day. Bruising is possible but uncommon. You can return to work and most daily activities immediately. However, you should avoid strenuous exercise, saunas, steam rooms, and alcohol for 24 hours.

How many Profhilo treatments do you need?

A complete treatment course consists of two sessions spaced four weeks apart. This allows hyaluronic acid to integrate into the skin and effectively stimulate collagen and elastin production.

For more advanced skin ageing, neck laxity, or multiple treatment areas, a third session may be recommended. Ongoing maintenance, performed every six months, helps sustain long-term skin quality.

Is Profhilo safe for all skin types?

Yes. Profhilo is suitable for all Fitzpatrick skin types, including darker complexions. Because it contains pure hyaluronic acid without chemical cross-linkers, the risk of adverse reactions is low. As with any injectable, it should only be performed by trained medical professionals following strict safety protocols.

What areas can be treated with Profhilo?

Profhilo is highly versatile and can be used on multiple high-movement or delicate areas prone to early ageing:

Face
Neck
Décolleté
Hands
Upper arms
Abdomen
Knees

These areas benefit from Profhilo’s ability to improve hydration, texture, elasticity and crepiness without adding volume.

How does Profhilo differ from fillers or skin boosters?

Profhilo is neither a filler nor a traditional skin booster. It sits in its own category, known as bioremodelling.

Dermal Fillers add volume and enhance contours.
Skin Boosters hydrate the skin superficially, resulting in a more radiant glow.
Profhilo hydrates deeply and stimulates collagen and elastin to improve the skin’s structure, firmness and elasticity.

It does not change facial shape or create artificial volume, making it ideal for natural-looking rejuvenation.

Frequently asked questions

Is Profhilo painful?

When can you expect to see results from Profhilo?

How long do Profhilo results last?

What is the downtime after a Profhilo treatment?

How many Profhilo treatments do you need?

A complete treatment course consists of two sessions spaced four weeks apart. This allows hyaluronic acid to integrate into the skin and effectively stimulate collagen and elastin production.

For more advanced skin ageing, neck laxity, or multiple treatment areas, a third session may be recommended. Ongoing maintenance, performed every six months, helps sustain long-term skin quality.

Is Profhilo safe for all skin types?

What areas can be treated with Profhilo?

Profhilo is highly versatile and can be used on multiple high-movement or delicate areas prone to early ageing:

Face
Neck
Décolleté
Hands
Upper arms
Abdomen
Knees

These areas benefit from Profhilo’s ability to improve hydration, texture, elasticity and crepiness without adding volume.

How does Profhilo differ from fillers or skin boosters?

Profhilo is neither a filler nor a traditional skin booster. It sits in its own category, known as bioremodelling.

Dermal Fillers add volume and enhance contours.
Skin Boosters hydrate the skin superficially, resulting in a more radiant glow.
Profhilo hydrates deeply and stimulates collagen and elastin to improve the skin’s structure, firmness and elasticity.

It does not change facial shape or create artificial volume, making it ideal for natural-looking rejuvenation.

Treatments

Profhilo®

Profhilo® at a glance

Best Results

Anaesthetic

Duration of Results

Procedure Time

Treatment Recovery

Skin Specialist

Risks & Complications

Back To Work

skin renewal solutions available to you

What Is Profhilo?

How Profhilo Works