What Is Platelet-Rich Fibrin (PRF)
PRF is a next-generation autologous (from your own body) treatment made by gently spinning a sample of your blood. Unlike Platelet-Rich Plasma (PRP), PRF is processed without anticoagulants, allowing the creation of a fibrin matrix that slowly releases growth factors, white blood cells, and stem cells over time. This supports natural healing, collagen production, and cellular renewal.
How Does PRF Work?
- Blood Collection: A small sample of your blood is drawn.
- Centrifugation: PRF contains concentrated platelets, leukocytes, and a three-dimensional fibrin matrix that facilitates slow release of growth factors. Unlike platelet-rich plasma (PRP), PRF is prepared without anticoagulants, resulting in immediate fibrin polymerisation during centrifugation.
- Fibrin Matrix Formation: The absence of anticoagulants forms a natural scaffold that gradually releases growth factors.
- Application: PRF is either injected or administered with microneedling to target the skin’s deeper layers.
This slow-release mechanism ensures that the benefits unfold over days and weeks, rather than just hours, like PRP.
Key Benefits of PRF
Skin Rejuvenation
- Smooths fine lines and deep wrinkles
- Improves tone, texture, and elasticity
- Reduces under-eye hollowness and crepey skin
- Offers subtle volume restoration naturally
Hair Regrowth
- Reactivates dormant hair follicles
- Slows the progression of hair thinning
- Improves scalp health for long-term results
Advanced Healing
- Accelerates tissue repair post-treatment
- Promotes healing of non-responsive wounds
Skin Renewal’s Doctor-Led Approach
Every PRF treatment at Skin Renewal is performed as part of a comprehensive, medically supervised programme. Our doctors customise each protocol according to your skin, health, and ageing profile.
We believe in combination treatments—PRF works best when paired with other treatments like:
- Microneedling: Devices like Dermapen stimulate natural collagen and elastin production, improving skin texture, firmness, and the absorption of active ingredients. It is especially powerful when paired with PRF.
- Carboxytherapy: Carboxytherapy increases the oxygen supply and blood flow to the skin, boosting cellular regeneration, reducing dark circles, and improving elasticity and radiance.
- Injectable Biostimulators: Biostimulation activates long-term collagen production for gradual, natural-looking skin tightening, volume restoration, and enhanced structural support.
- Botulinum Toxin: Botox® and Dysport® smooth dynamic wrinkles by relaxing targeted facial muscles—they are especially effective for crow's feet, forehead, and frown lines.
- Dermal Fillers: Hyaluronic Acid-based dermal fillers restore lost volume, smooth deep wrinkles, and enhance facial contours, delivering instant rejuvenation with natural-looking results.
- Laser Treatments: PRF can be done immediately after laser treatments such as Laser Genesis, Pico Toning and FSR for ultimate regeneration benefits.
Skincare & Supplements
Skin Renewal offers a carefully formulated professional skincare range designed to work synergistically with advanced treatments like PRF. Our targeted products—such as the HA Gel with Peptides, Radiance Cream, and Antioxidant Serum with Phloretin—are designed to support post-treatment recovery, stimulate collagen, and restore hydration. These formulations are rich in clinically active ingredients that protect the skin barrier, reduce inflammation, and amplify the regenerative effects of your treatment. Incorporating them into your homecare routine ensures longer-lasting results and radiant, healthier-looking skin.
Internal support through targeted supplementation is highly recommended to further enhance the regenerative effects of PRP and PRF treatments.
- Omega-3 fatty acids are vital in reducing inflammation and supporting skin healing from within.
- Marine collagen helps to improve skin density and elasticity, reinforcing the structural integrity restored during treatment.
- Zinc and Vitamin C boost the body’s natural regenerative processes, aiding in collagen synthesis and immune function.
- NAD with Resveratrol offers powerful antioxidant protection while promoting cellular energy and DNA repair—ideal for clients seeking to optimise skin rejuvenation at a cellular level.
Differences Between PRP and PRF Treatments
