Resteeme | Biostimulation | Injectable Treatments

Resteeme™

Ageing is a quiet, progressive process that begins deep within the skin long before it becomes visible on the surface. As the years pass, the body’s natural production of collagen and elastin slows, weakening the very framework that keeps skin firm, smooth, and resilient. What was once dense and structured gradually becomes thinner, softer, and less supported, leading to fine lines, laxity, and a loss of youthful definition. True rejuvenation, therefore, is not about masking these changes but about restoring the skin’s strength from within. This is where advanced regenerative treatments, such as Resteeme™, offer a more intelligent and lasting approach to ageing skin.

Resteeme™ at a glance

Best Results

1-4 Treatments

Anaesthetic

Local Anaesthetic (depending on area)

Duration of Results

Up To 12 Months

Procedure Time

30-60min

Treatment Recovery

1-3 Days

Skin Specialist

Doctor

Risks & Complications

Low

Back To Work

Same Day

What Are Biostimulators?

Biostimulators are injectable or topical regenerative treatments that encourage your skin to repair and renew itself. Unlike traditional dermal fillers, which provide immediate volume, biostimulators work gradually, delivering:

Long-term collagen stimulation
Improved skin firmness and elasticity
Stronger, healthier skin structure
Natural-looking rejuvenation

The Role of Glycation in Skin Ageing

While collagen loss is well known as a part of ageing, glycation is another key factor that significantly accelerates skin ageing.

Glycation occurs when excess sugar in the body binds to proteins such as collagen and elastin. This process forms harmful compounds known as advanced glycation end-products (AGEs), which cause collagen fibres to become:

Rigid and brittle
Less elastic and more prone to damage
Unable to support healthy skin structure

Over time, this leads to:

Increased skin laxity
Deeper lines and wrinkles
Dull, uneven skin texture
Reduced the ability of the skin to repair itself

Glycation is influenced by factors such as diet, lifestyle, stress, and sun exposure, making it a critical (but often overlooked) driver of premature ageing.

How Resteeme™ Targets Glycation and Skin Regeneration

What sets Resteeme™ Biostimulators apart is their ability not only to stimulate collagen but also to support the skin in combating the effects of glycation. Through advanced regenerative technology, Resteeme™ helps to:

Support healthier, more functional collagen production
Improve skin resilience against glycation-related damage
Enhance cellular renewal and repair processes
Promote stronger, more flexible dermal structures

By addressing both collagen loss and glycation, Resteeme™ provides a more comprehensive approach to skin rejuvenation, helping the skin function more youthfully, not just look better.

Why Anti-Glycation Matters in Modern Anti-Ageing Treatments

Modern aesthetic treatments are evolving beyond surface correction to focus on true skin health and longevity. Incorporating anti-glycation strategies into your treatment plan can:

Slow the visible ageing process
Improve long-term treatment outcomes
Enhance skin quality and durability
Support a more youthful skin structure over time

The Science Behind Resteeme™ Technology

Resteeme™ is built on advanced regenerative science, combining skin biology, structural support, and cellular stimulation.

Collagen Activation at a Cellular Level

Resteeme™ works by stimulating fibroblasts (the cells responsible for producing collagen and elastin). Over time, this leads to:

Increased skin density
Improved elasticity
Reduction in fine lines and skin laxity

Skin Bio-Dynamics & Structural Alignment

The treatment respects the skin’s natural architecture, including fibre orientation and tension lines. This allows for:

More natural movement of the skin
Better integration into tissue
Enhanced long-term results

Regenerative Skin Renewal

Rather than delivering a quick fix, Resteeme™ supports:

Tissue repair and regeneration
Improved microcirculation
Stronger dermal support networks

Trehalose Technology: Enhancing Longevity & Skin Protection

One of the unique components of Resteeme™ is Trehalose. This advanced protective sugar molecule plays a vital role in enhancing treatment outcomes. Trehalose is known for its ability to:

Protect hyaluronic acid (HA) from degradation
Prolong the lifespan of HA within the skin
Support longer-lasting hydration and structural support
Help stabilise the skin’s cellular environment

Why This Matters

By combining hyaluronic acid with Trehalose, Resteeme™ delivers more than just hydration; it creates a protective and regenerative environment within the skin. This results in:

Longer-lasting treatment benefits
Improved skin resilience and hydration
More efficient collagen stimulation over time

Who Is This Treatment For?

Resteeme™ Biostimulators are ideal for:

Early signs of ageing (fine lines, mild laxity)
Thinning or weakened skin
Loss of skin firmness and elasticity
Patients want natural, subtle results
Individuals looking for preventative anti-ageing treatments

frequently asked
questions

Are Resteeme™ treatments available at all Skin Renewal Clinics?

Resteeme™ treatments are available in Gauteng at the Morningside, Parkhurst, Rosebank, Bedfordview, Fourways, West Rand, Irene, Waterfall, Lynnwood, and Brooklyn clinics, as well as in the Western Cape at Cape Quarter, Claremont, Constantia, Century City, Stellenbosch, Paarl and Willowbridge clinics, and Kwa-Zulu Natal at the Ballito, Durban and Umhlanga clinics.

How long do Resteeme™ Biostimulator results last?

Results from Resteeme™ treatments develop gradually and can last several months, depending on your skin condition, age, and lifestyle. Because the treatment stimulates your own collagen, the improvements tend to be longer-lasting compared to treatments that only provide temporary correction.

At what age should you start biostimulator treatments?

There is no fixed age to begin. Many patients start in their late 20s to early 30s as a preventative approach, while others begin later to restore collagen loss. The ideal timing depends on your skin quality and long-term skin goals rather than age alone.

Can Resteeme™ be combined with other aesthetic treatments?

Yes, Resteeme™ is often incorporated into combination treatment plans. It pairs well with treatments targeting different layers of the skin, helping enhance overall results and support more comprehensive skin rejuvenation.

Is Resteeme™ suitable for sensitive or thin skin?

Resteeme™ is generally well-suited for delicate or thinning skin, as it focuses on strengthening the skin from within rather than adding volume. Your Skin Renewal doctor will assess your skin to ensure the treatment is appropriate for your specific needs.

How soon can you return to normal activities after treatment?

Most patients can return to normal daily activities shortly after treatment. Your Skin Renewal doctor may recommend avoiding strenuous exercise, excessive heat, or active skincare ingredients for a short period.

Is there a difference between biostimulators and skin boosters?

Yes, while both improve skin quality, biostimulators focus more on activating collagen production and long-term regeneration. In contrast, skin boosters primarily improve hydration and surface skin texture.

Are the results of Resteeme™ noticeable immediately?

Some patients may notice early improvements, but the most significant results develop progressively as collagen production increases over time.

How do you know if Resteeme™ is right for you?

The best way to determine suitability is through a professional consultation. Your practitioner will assess your skin, discuss your goals, and recommend whether Resteeme™ aligns with your treatment plan.

Is Resteeme™ treatments painful?

Resteeme™ biostimulator treatments are not considered painful. Most patients experience only mild discomfort, as numbing agents are used to improve comfort, and any tenderness afterwards is usually short-lived.

Is Resteeme™ Biostimulator treatment safe?

Yes. Resteeme™ biostimulators are considered safe when performed by a qualified, experienced medical professional, which is why a doctor-led approach is so important.

Can Resteeme Be Used on All Skin Types?

Yes. Resteeme biostimulators are generally suitable for all skin types.

Because this treatment works by stimulating your body’s own collagen production, rather than introducing foreign volume or pigment-altering substances, it is typically well tolerated across different skin tones and skin conditions.

Frequently asked questions