Frequently Asked Questions

At Skin Renewal, customized intravenous vitamin therapy – as well as other non-vitamin infusion combinations- of the following vitamins, minerals and antioxidants are combined depending on the cocktail chosen for therapy: Glutathione, Vit C, Vit B6 Pyridoxine, Vit B 12, Magnesium Sulphate, Manganese Sulphate, Zinc Sulphate and Selenium, EDTA and PPC (phosphatidylcholine). These vital nutrients help treat a wide variety of health conditions. This direct form of highly effective treatment is administered in our Infusion Suites, a comfortable and relaxing environment located inside our centres.

At Skin Renewal our IV Solutions are:

  • Made in a STERILE and registered lab
  • Not contaminated with unwanted "floaters", and
  • Do NOT cause any unwanted side effects
  1. All infusions are done by our registered nurses or doctors
  2. An ACLS certified Doctor is always present in the clinic when infusions are being done
  3. Our infusion doctors all have ACLS certification (acute cardiac life support certification) and are well prepared should any unwanted effects occur.
  4. A doctor or an experienced registered nurse performs the infusions ▪️Our registered nurses all have BLS (Basic Life Support) training.
  5. We have emergency equipment such as AED, emergency drugs, etc present in the infusion ward
  6. Strict adherence to sterile protocols is adhered to.

Scientific research has demonstrated that a variety of conditions can be treated from the use of IV nutrition/supplementation. A few of the conditions that may be helped using IV nutrition techniques include hypertension, COPD, asthma, fibromyalgia, chronic fatigue syndrome, diabetes, hepatitis, and even the common cold.

Additional conditions that may be helped include:

  • Poor detoxification
  • Immune Enhancement
  • Anxiety and Panic Attacks
  • Managing Increased stress
  • Depression and Mood Swings
  • Multiple Sclerosis
  • Memory problems and brain fog
  • Neuropathy
  • Heart disease/cardiovascular disease
  • Poor circulation
  • Arthritis
  • Cold, flu, and other minor viral infections
  • Candida
  • Hepatitis
  • Digestive disorders - intestinal malabsorption
  • Post-gastric bypass
  • Pre/post-surgery
  • Heavy metal toxicity
  • Macular Degeneration


  • Skin Brightening
  • Improve athletic performance and endurance
  • Thyroid support

At times, such as in times of stress, higher doses of vitamins and antioxidants are needed. They are also needed to combat viral illness, immune dysfunctions, and cancer. Oral intake of such high doses is simply not possible due to cellular and mechanical absorption limitations from the digestive process.

Skin Renewal is the perfect place for women and men to secure integrative and holistic health care from providers who give personalized care, partner with the patient to focus on the root cause of their illness, support their recovery, and help them maintain good health. For those that can make the journey, we are happy to welcome new patients to experience IV infusions at any of our Skin Renewal clinics in Cape Town, Pretoria, Johannesburg, and KZN.

An initial consultation with the Integrative practitioner at Skin Renewal is mandatory and will be approximately 20 minutes. The cost of the initial diagnostic IV consultation is R650 during which the Doctor will assess your overall health and medical history. Your Skin Renewal practitioner will begin working on a unique prescription plan which will include an appropriate IV infusion therapy. Your practitioner may also prescribe additional nutraceutical supplements such as Vit C and Alpha Lipoic Acid to complement the IV infusion.

All these recommendations will be summarized on a sheet/print out which you can take home with you. At Skin Renewal, we have a great professional team made up of medical doctors and registered nurses and therapists to support you at any time. An added bonus is that you are not only improving your health and well-being, any nutraceuticals/ supplements purchased will go towards loyalty points at any Skin Renewal branch.

For Skin Brightening, it is recommended to have IV infusions twice a week in the first month in order to get the full benefit. After this period, infusions can be done weekly until your desired skin tone and results are achieved. Thereafter a session every month to maintain results.

For most infusions, weekly IV therapy for a period of 10 to 20 sessions depending on the condition is usually recommended. For Chelation therapy for the arteries of heart, twice weekly infusions are recommended.

The infusion will be put up and monitored by our trained registered nurses. A doctor will always be available on site for assistance if necessary

IV Therapy is a minimally invasive treatment that is well tolerated by most people. A very small ‘butterfly’ needle or a micro-catheter/jelco, is used to infuse the prescribed supplements. There is a low risk of serious adverse side effects which may include a slight after-taste of supplements shortly after the infusion. Urine may also have a strong odor or color shortly after completion. Some patients may also experience a sensation of warmth and flushing or feel a cooling sensation as the IV is administered. Intravenous supplements are very safe, beneficial, and easy for applicants.

Spend an hour every week giving your body what it needs.

Make an appointment to consult with the medical practitioner, who are also integrative doctors, and they will assist you in determining what IV infusion would be appropriate for you. In addition, your risk factors will be evaluated and how best to prevent any problems or conditions, that you may be susceptible to, will be recommended.

IV infusions at Skin Renewal are not suitable for patients who are:

  • Pregnant or breast-feeding
  • Menstruating
  • On mood stabilizers/epilepsy medication
  • On blood thinners such as Warfarin, Plavix, Heparin
  • Allergy to vitamin (any kind)
  • Have Diabetes
  • Blood-iron disorders including thalassemia
  • Blood-iron disorders including hemochromatosis
  • Sickle cell disease
  • A metabolic deficiency called “glucose-6-phosphate dehydrogenase deficiency” (G6PDD)
  • Kidney stones, or a history of kidney stones
  • Patient with cardiovascular problems
  • Heart block
  • Angioplasty: Straight before or straight after Angioplasty, a heart procedure.

The medications that are contraindicated with IV infusions are mostly mood stabilizers prescribed for bipolar conditions and epilepsy. Also Benzodiazepines (Valium etc), prednisone and a few diuretics:

  • Gabapentin
  • Prednisolone
  • Lorazepam
  • Diazepam
  • Carbamazepine
  • Sodium Valproate
  • Acetazolamide
  • Carbamazepine
  • Clobazam
  • Diazepam
  • Ethosuximide
  • Fosphenytoin Sodium
  • Gabapentin
  • Inovelon
  • Lacosamide
  • Lamictal
  • Lamotrigine
  • Levetiracetam
  • Lorazepam
  • Oxcarbazepine
  • Phenytoin
  • Phenytoin Sodium
  • Piracetam
  • Prednisolone
  • Pregabalin
  • Primidone
  • Rivotril
  • Sodium Valproate
  • Tiagabine hydrochloride monohydrate
  • Topamax
  • Trobalt
  • Vigabatrin
  • Zarontin
  • Zebinix
  • Zonegran

Glutathione is a tripeptide (made of 3 amino acids) that is produced in the body in small amounts.


  • Is an extremely effective antioxidant, which as we know means that it reduces free radicals in the body reactive oxygen compounds.
  • It has also been shown to bind to toxic substances in the body especially the liver and assists in flushing the toxins out of the system.
  • Glutathione is also an important player in the synthesis and repair of DNA, protein synthesis, and enzyme activation.

The body produces glutathione naturally, and research has shown healthy intake of Vitamin C boosts its production. If glutathione levels are normal, the body’s ability to fight neurological disorders like Parkinson’s disease is strong. If they are low, you are susceptible to a revolving door of conditions. Low levels are associated with hepatic dysfunction, immune dysfunction, cardiac disease, premature aging, and death.

Every system in the body is affected by the Glutathione system, including;

  • The immune system,
  • The gastrointestinal system
  • The nervous system

There are few other factors that are predictive of our life expectancy as is our level of cellular glutathione. Glutathione levels in our cells are predictive of how long we will live. Glutathione is called the “Master Antioxidant” without it- other important antioxidants such as Vitamin C and E cannot do their job adequately to protect your body against disease. No other antioxidant is as important to overall health as glutathione. It is the regulator and regenerator of immune cells and the most valuable detoxifying agent in the human body. Glutathione is water-soluble and easily destroyed by the body systems. An infusion of Intravenous Glutathione directly distributes this master antioxidant to every cell in our body and skin without being destroyed by our digestive tract.

Oral glutathione breaks down in the stomach, losing its potency via the digestive system. Your body’s own enzymes break down the peptide bonds that hold the amino acids in glutathione together. But with intravenous infusion therapy, glutathione goes directly through the bloodstream to the cells. Extra glutathione is used by the body for strengthening the immune and other systems, and can also have a positive effect on various skin conditions including acne. As you can see, glutathione should be an important part of any supplementation regimen.

These benefits can be received through fairly reasonable dosages of Glutathione, making it an excellent addition to any IV supplementation regimen. At higher dosages, glutathione may also be effective at lightening skin. The intensive Anti Oxidant Infusion will boost your energy levels, heighten your immune system and illuminate your skin, literally, from the inside out!

  • Smokers, alcohol users, adults age 40 years and above,
  • If you exercise excessively/bodybuilders;
  • If you have the following:
  • Low sperm count, liver problems and cataracts,
  • If you are recovering from chemotherapy, the immunocompromised, low immune system
  • If you are exposed to chemicals and pesticides,
  • If you want an even-toned skin
  • Melasma/hormonal pigmentation problems.

IV glutathione is particularly effective in treating neurodegenerative diseases. Neurological disorders can result when free radicals destroy neurons that produce dopamine, a vital neurotransmitter. Glutathione inhibits free radical production, thus slowing the effects of these conditions while improving brain function. In fact, a number of clinical studies over the past two decades have demonstrated that glutathione is severely depleted in patients with Parkinson’s and other neurodegenerative diseases.

IV glutathione infusions significantly reduce oxidative damage and death of dopamine-producing neurons, helping to improve patients’ symptoms and quality of life.

IV glutathione may improve the following:

  • Parkinson’s disease
  • Multiple sclerosis
  • Alzheimer’s disease
  • Strokes
  • Fibromyalgia / Chronic Fatigue Syndrome
  • Liver disease including Hepatitis B and C

Other antioxidants in the body depend on glutathione as well. Glutathione recycles vitamins C and E after they have been oxidized—therefore playing a decisive role in their normal function.

  • Ultraviolet and Other Radiation
  • Household Chemicals
  • Paracetamol Poisoning
  • Cigarette Smoke
  • Exhaust from Motor Vehicles
  • Heavy Metals
  • Other Environmental Toxins
  • Viral Infections
  • Surgery
  • Inflammation
  • Burns
  • Septic Shock
  • Dietary Deficiencies of GSH Precursors
  • Enzyme Cofactors

Magnesium is one of the most important minerals; your body needs it to perform over 300 biochemical reactions necessary to sustain life. The deficiency of magnesium in your body can cause or worsen multiple medical conditions. Given as an IV, the Magnesium Drip effectively enhances the function of muscular and nervous systems. Many people are deficient in magnesium without even knowing it. You would be surprised at the difference patients feel after they have the Magnesium Drip; their jittery nerves are calmed and their tense muscles are relaxed instantly.

Treating deficiency of magnesium in the body can not only manage current conditions but also prevent disorders from developing in the future.

There are numerous conditions that can benefit from a Magnesium infusion:

  • Anxiety: Often anxiety is treated with psychiatry through prescription medication. Many doctors do not take into account the fact that a lack of magnesium can stress your body and create or exacerbate anxiety. An estimated 50% of people do not have an adequate amount of magnesium in their bodies. Magnesium Infusion may prove effective in the treatment of anxiety.
  • Cardiac Arrhythmias: Magnesium deficiency causes major stress on the muscular system. The most important muscle in the human body is the heart. There is an intricate connection between magnesium and the heart’s electrical stability. Lacking magnesium may cause irregular heartbeats commonly known as arrhythmias. Magnesium IV therapy results in relaxation of the heart and dilates blood vessels. This allows the heart to work more efficiently.
  • Chronic Fatigue Syndrome: Some reports suggest that magnesium may be helpful in ameliorating the symptoms of chronic fatigue syndrome.
  • Fibromyalgia: A severe deficiency of magnesium can cause the muscles in the body to be in a constant state of spasm. Since the muscular and nervous systems are both involved in the symptoms of fibromyalgia, there is believed to be a link between the disease and a deficiency in magnesium. Balancing the levels of magnesium in your body through Magnesium IV infusions may improve and deter the symptoms of Fibromyalgia.
  • Hypertension: Magnesium is a powerful vasodilator. When blood vessels are dilated, blood pressure comes down dramatically.

Vitamin B12 is a nutrient that helps keep the body's nerve and blood cells healthy and helps make DNA, the genetic material in all cells. Vitamin B12 also helps prevent a type of anemia called megaloblastic anemia that makes people tired and weak. Vitamin B12 can promote red blood cell formation and regeneration, improve physical strength, repair damaged nerves, and maintain the health of our nervous system. It can also concentrate on improving the memory-weakened state. Vitamin B12 helps to relieve numbness, pain, and paresthesia.

B-complex is the agent that responds with the proper functioning of the most important processes in the body, such as cell growth and division, the health of the skin, the normal development of the immune and nervous system, and the metabolic process. They play a major role in the activities of enzymes, proteins that regulate chemical reactions in the body, which are important in turning food into energy and other needed substances.

Some of the many benefits of the Vitamin B-complex are:

  • Improves Metabolism
  • Maintains Normal Skin Function
  • Produce happy hormone
  • Reduces Water Retention
  • Promotes a Normal Appetite
  • Increases Red Blood Cell Production
  • Improves Liver Function
  • Boosts Production of Energy

Vit C is a remarkable substance to use intravenously when the normal oral dose needs to be exceeded. Patients can get up to 10 times the nutrients in one IV treatment as they could get orally in one day. A good example of this is the use of Vitamin C when trying to overcome a cold due to some sort of virus. The antiviral effects of Vitamin C are seen when blood levels are around 10-15 mg/dL. This level is achievable with IV therapy but not orally. Oral dosage typically results in blood levels around 1.2-4.0 mg/dL as compared to IV therapy where blood levels of Vitamin C can reach 50-90 mg/dL.

Diarrhea may occur when taking doses of 5 or more grams per day, and bowel tolerance is a maximum of 10 grams per 24 hours. Vitamin C in dosages of 25 grams or more takes on a therapeutic role that is safe and effective in treating many clinical conditions. In studying the physiological role of Vitamin C, one realizes that it does a lot more than merely stop humans from getting scurvy or giving them expensive urine. It is well known for immune stimulation, but also plays a part in collagen formation, hormone production and liver detoxification, wound healing, and slowing the metastatic spread of carcinomas.

Zinc is an essential nutritional requirement and serves as a cofactor for more than 70 different enzymes including carbonic anhydrase, alkaline phosphatase, lactic dehydrogenase, and both RNA and DNA polymerase. Zinc facilitates wound healing; helps maintain normal growth rates, normal skin hydration, and the senses of taste and smell.

Zinc resides in muscle, bone, skin, kidney, liver, pancreas, and retina, prostate, and particularly in the red and white blood cells. Zinc is an important chemical essential for human functioning. Zinc nutrition deficiency is insufficient availability of zinc in the diet or can be caused due to the malabsorption of zinc by the body. This condition is prevalent in young children, pregnant women, breastfeeding mothers, and the elderly. Zinc plays a vital role in many aspects of the immune system. It helps in cell division, clotting, healing wounds, DNA synthesis, growth and development of the fetus, and protein synthesis.

The inherent gastrointestinal problems, liver disease, kidney diseases, and certain other conditions and drugs can prevent zinc absorption by the body causing a zinc deficiency.

The top five signs of zinc deficiency are:

  • Compromised immune system: Zinc affects cell activities. Zinc deficiency can cause reduced or weakened antibodies and compromise the immune system. Thus the deficient person will be prone to infection or flu.
  • Diarrhea: A compromised immune system makes one susceptible to infection. One of these infections is a bacteria that causes diarrhea.
  • Hair loss and skin lesions: Zinc is important for normal cell growth. Zinc nutrition deficiency weakens the cells, which can result in hair loss in the case of cells on the scalp and lesions on the skin. This is one of the prominent signs of zinc deficiency.
  • Loss of appetite and/or anorexia: A deficiency of zinc causes decreased loss of appetite. If zinc deficiency is not identified and treated, decreased loss of appetite can eventually lead to anorexia.
  • Impairment of cognitive and motor functions: Zinc deficiency in a pregnant mother can not only weaken the mother but can also cause damage to the fetus’s neurological system, impairing the motor skills and cognitive skills of the infant.
  • Other signs of zinc deficiency are reduced fertility, rashes on the skin, spots on fingernails, sleep disturbance, loss of sex drive, loss of taste or smell, and in some cases mild anemia.

Selenium is a mineral that is needed in small amounts by the body to help regulate thyroid hormones and support a healthy immune system.

  • One of the selenium’s most important roles is as an antioxidant helping to prevent cell damage due to free radicals.
  • Selenium is incorporated into molecules of an enzyme called glutathione peroxidase (GPX). This vital enzyme protects red blood cells and cell membranes against undesirable reactions with soluble peroxides. Good selenium nutrition is of key importance for antioxidant defense as well as efficient energy metabolism.
  • Several research studies have demonstrated the benefits of selenium supplementation in treating autoimmune thyroid conditions. One study found that selenium supplementation had a significant impact on inflammatory activity in thyroid-specific autoimmune disease, and reducing inflammation may limit damage to thyroid tissue. This may be due to the increase in glutathione peroxidase and thioredoxin reductase activity, as well as the decrease in toxic concentrations of hydrogen peroxide and lipid hydroperoxides which result from thyroid hormone synthesis. Selenium is required for the activation of an enzyme called glutathione peroxidase. This enzyme is an antioxidant that quenches hydroperoxides, "high energy" oxygen-containing molecules that are produced during the metabolism of fat and that are highly toxic to cells.
  • Recent research showed that selenium could reduce the severity of some cancers. This is thought to be due to selenium inducing "apoptosis" (programmed cell death) in cancer cells.

Manganese is a trace mineral that is present in tiny amounts in the body. It is found mostly in bones, the liver, kidneys, and pancreas. Manganese helps the body form connective tissue, bones, blood-clotting factors, and sex hormones. It also plays a role in fat and carbohydrate metabolism, calcium absorption, and blood sugar regulation. Manganese is also necessary for normal brain and nerve function.

Manganese is a component of the antioxidant enzyme superoxide dismutase (SOD), which helps fight free radicals. Free radicals occur naturally in the body but can damage cell membranes and DNA. They may play a role in aging, as well as the development of a number of health conditions, including heart disease and cancer. Antioxidants, such as SOD, can help neutralize free radicals and reduce or even help prevent some of the damage they cause.

Manganese may help with some of the following conditions:

Osteoporosis: Manganese is one of several trace elements (including vanadium and boron) that are necessary for bone health.

Arthritis: People with arthritis tend to have low levels of SOD (an antioxidant that helps protect the joints from damage during inflammation). Some experts theorize that manganese may increase SOD levels.

Premenstrual syndrome (PMS): In one well-designed clinical study, women who ate 5.6 mg of manganese in their diets each day had fewer mood swings and cramps compared to those who ate only 1 mg of manganese.

Diabetes: Some studies seem to show that people with diabetes have low levels of manganese in their blood.

Epilepsy: Several clinical studies suggest that people who have seizure disorders have lower levels of manganese in their blood.

7 Reviews (average: 5 out of 5)

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*Please note results may vary by individuals.
Review -Great service for IV Infusion
Reviewed on 8 October 2018 by Anonymous

I have had a great experience with Liana Hanekom, the nurse. Thank you very much for the great service. You are professional and kind. Keep up the great work.

Review -Customer Service
Reviewed on 14 September 2018 by Anonymous

The staff is very friendly and helpful. I personnaly appreciate the fact that you get assigned to your own therapist from day one of your treatments until the end. My therapist Maries has been doing a brilliant job with my skin as well as checking up on my progress every now and then. My "black skin"is definetly in good hands.

Review -Dr Sedicka
Reviewed on 4 September 2018 by Anonymous

I am highly satisfied with my monthly visits to have my cocktail and Vit C infusion. Dr Sedicka displays, knowledge, empathy, care at a high level. I have recommended her to my wife and 2 daughters. Dr Sedicka is an asset I value. Thank you

Review -Awesome service
Reviewed on 29 October 2017 by Marissa

I had an appointment with Dr Lestonn Lawn - he was awesome and very understanding and the results of my procedure are fantastic.

Review -Mrs SA Finalist Sponsor Review: Merlin Norman
Reviewed on 16 October 2017 by Merlin Norman

What a spoil it has been to be treated by the Renewal Institute Willowbridge. A loved institution which provides a wide range of treatments and skin care products for all types of skin ensuring your skin is kept beautiful and glowing for longer.

My treatments have rejuvenated my skin and enhanced the texture and appearance #ClickedonSkin from the inside out. Being treated by expert skin care specialists my treatments and facial experiences have addressed my personal skin care needs and I am loving the results.

I am truly humbled by the personal support and care I have received from The Renewal Institute.

Review -Excellent service from Nurse
Reviewed on 9 September 2017 by Fazlin Swanepoel

I would like to commend the nurses at Fourways on her excellent service. She is professional, knowledgeable and caring. I would definitely recommend her services.

Review -Mrs SA Finalist Sponsor Review: Michelle Bekker
Reviewed on 22 August 2017 by Michelle Bekker

My experience with Dr. Graham and therapist has been wonderful. I love the beautiful, relaxed and friendly ambience. The information provided during consultation and the treatments have truly been spectacular. I absolutely love having facial peels and laser treatment and my skin has never felt more rejuvenated. I am feeling so confident in my skin after my treatment that I am happy to go without any foundation. Thank you for taking care of my skin. No more dry skin! #ClickedonSkin

Sharon Izak Elaine Chat staff ) WhatsApp