Skin Renewal

Cosmelan Depigmentation at a Glance

Best Results 1 - 2

Duration of Results 8 - 12 months

Treatment Recovery 7 - 10 days

Risks & Complications Medium

Anaesthetic None

Procedure Time 30 mins

Skin Specialist Therapist

Back To Work Next day - 4 days

Cosmelan treatment guarantees the improvement of the anti-aesthetic skin blemishes with a very high safety margin. Cosmelan Depigmentation treatment’s principal action is the elimination of melanin patches on the face - melasma .Also called chloasma if the pigmentation occurs with pregnancy Cosmelan Depigmentation treatment involves a very versatile, dynamic process which is easily adapted to the needs of each individual patient.

At Skin Renewal, to improve results with Cosmelan, a Mesoestetic Melanostop Peel is applied immediately before the mask treatment at no extra cost.

Frequently Asked Questions

1
Are Cosmelan treatments available at all Skin Renewal branches?
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The Cosmelan treatment is available in Johannesburg at Fourways, Parkhurst, Morningside, Bedfordview, West Rand and Illovo as well as in Pretoria at Brooklyn and Irene and in the Western Cape at Cape Quarter, Claremont, Constantia, Stellenbosch, Willowbridge, Paarl and KwaZulu-Natal at Durban & Umhlanga.
2
What does Cosmelan Depigmentation treat?
Read More
Skin ageing caused by systematic sun exposure, facial blemishes due to excessive pigmentation and, in general, imperfections caused by melanin, are more and more common problems today… “Dark blemishes”, especially on hands and face, are one of the greatest aesthetic concerns of modern men and women… It will only be possible to remove the anti-aesthetic skin blemishes and recover the smoothness of the skin, bringing back its luminosity, with a treatment that has a direct effect on the intimate formation process of the pigment (melanin).
3
What does Cosmelan Depigmentation work?
Read More
Cosmelan Depigmentation treatment action mechanism is based on the inhibition of tyrosinase, a basic enzyme in the melanin formation process. Several of the substances present in the Cosmelan® formula act by blocking this enzyme, or even by inverting the metabolic process of the transformation chain. Melanogenesis comprises the following stages:
TYROSINE proceeds to DOPA by means of TYROSINASE.
DOPA proceeds to DOPAQUINONE by means of TYROSINASE.
DOPAQUINONE proceeds to PHAEOMELANINE and EUMELANIN by means of oxidation and cyclization.
4
What are the advantages of Cosmelan Depigmentation?
Read More
The Cosmelan Depigmentation treatment offers a series of major advantages and benefits compared with other types of depigmentation products found in the market:
- Very effective in all types of Melasma especially deep seated severe Melasma or post inflammatory hyperpigmentation PIH
- Effective for pigmentation that has failed to resolve after traditional skin lightening topical products
- Effective for pigmentation that has failed to resolve after traditional treatments such as superficial peels
- Rapid and easy depigmenting action
- Compatible with ALL skin types (Fitzpatrick I – VI)
- Light peeling effect
- Treatment can be used all year round
- Beneficial for acne patients and the PIH after acne has resolved
- Does not contain Hydroquinone or TCA
- High safety margin
5
What results can be expected from Cosmelan Depigmentation?
Read More
In 99% of the cases, the disappearance of the blemishes improves by 95%...
ONE WEEK after starting the Cosmelan® Depigmentation treatment, a noticeable significant improvement of the skin is observed! The reduction of the treated blemish is detected and the appearance of new luminous and rejuvenated skin is present.
At the end of the Cosmelan® Depigmentation treatment, the blemishes start to disappear altogether, so that, although the patient may be able to “locate” the place where the spot was, the truth is that the pigmentation will have disappeared and nobody will be able to see it just by looking at it
6
What conditions can be treated with Cosmelan Depigmentation?
Read More
Cosmelan works by blocking the process that causes hyperpigmentation. It works for:
- Melasma
- Brown Spots
- Blotchy Skin
- Hyperpigmentation
- Post-inflammatory hyperpigmentation of dermatitis and acne cars
- Prevention of hyperpigmentation post-laser and post-peel
7
What are the active ingredients in Cosmelan Depigmentation?
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Cosmelan 1 – mask
Azelaic Acid, Kojic Acid, Phytic Acid, Ascorbic Acid, Arbutine, and Titanium Dioxide
Cosmelan 2 – Maintenance Cream (30g)
Titanium Dioxide, Kojic Acid, Phytic Acid, Ascorbic Acid
Mesoestetic Hydra Vital Factor K Cream (50ml)
Hydro nutritional cream for face and neck. Hydroviton, VItamin K, Vitamin E, Amniotic fluid, Glycerine, Silicone oil.
8
What precautions must be undertaken before proceeding with Cosmelan?
Read More
Important: it must be known if the patient has undergone any previous treatments, especially with glycolic acid. If confirmed, any treatment, especially Glycolic Acid, must be eliminated at least, one week prior to using Cosmelan Depigmentation treatment.
The Cosmelan® Depigmentation treatment initiated at the medical office must be continued at home, on a daily basis, according to the guidelines indicated.
The treatment must not be interrupted under any circumstances, during the whole time prescribed.
It is completely forbidden to combine the Cosmelan® Depigmentation treatment with other depigmentation treatments, as the appearance of undesired effects cannot be guaranteed.
Treatment control visits are recommended. 8 days after beginning of treatment, 15 days after, and a follow up visit every month thereafter.
9
What can be expected after a Cosmelan treatment mask?
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First and second day
During the first two days of the treatment, the skin may turn red. If the skin is very sensitive, the patient may experience an itching feeling. Slight burning and tightening of the skin is also absolutely normal, especially during the first 24 to 48 hours after starting the treatment. To relieve these problems, it is advisable to apply the Mesoestetic Hydra-vital factor K whenever necessary.
Reddening of the Skin. The reddening that occurs on the face after applying the Mesoestetic Cosmelan mask treatment is similar to the effects of day-long exposure to the sun in the snow without protection. (Intense reddening in photo type I and II and practically non existent in photo type IV and V).
Flaking may occur on all skin types (and more intensely in photo types I and II) between the second and third day. In this case it is advisable to apply the Mesoestetic® Hydra-vital factor K cream, repeating this every two hours on the day when the flaking is most intense repeating this every 2 hours until it improves. Do not pull on the flakes. Do not rub or scratch the skin. If necessary flakes can be cut off. Do not use exfoliants, scrubs or peels. Avoid steam baths, saunas and swimming in a hot spring for 2 weeks following treatment. It is advisable to wait until the initial flaking period is over before starting to apply make-up again.
Warning
If a severe skin reaction results from treatment do not proceed with maintenance treatment. Similarly, if scab formation is seen or if the skin is accidentally injured during the treatment period it is advisable to interrupt application of maintenance treatment. Use only Hydra-vital factor K and Sunscreen until the skin has settled and then again proceed with the maintenance treatment schedule. If in doubt, please contact your doctor at Skin Renewal immediately.
Third and fourth day. After the third or fourth day, the skin appears healthy and luminous and the marks begin to fade.
10
What can be expected after the home application of Cosmelan 2?
Read More
HOME TREATMENT – Cosmelan Maintenance Cream
The second phase of the Cosmelan consists of a home maintenance cream Cosmelan with the intention of securing the depigmentation by association of agents such as Kojic Acid, Phytic Acid, and Vitamin C. We have added a physical agent to block the sun and guarantee that the UV rays do not keep on aggravating unwanted cutaneous hyper pigmentation.
11
What does the stabilization period of a Cosmelan depigmentation treatment mean?
Read More
The period following the initial 6 month treatment process, is called the STABILISATION period, and this can ideally be extended up to one year. Every effort should be made to continue treatment throughout the first summer. Even if the treatment is a great success, long term success depends on how well the protocol is followed, during both the treatment and stabilization phases. VERY GOOD sunblock is essential at all times.
12
What are the complimentary products that can be used with Cosmelan?
Read More
Mesoestetic Vitamin C ampoules: use twice weekly before applying the Cosmelan 2 cream.
Hydra Vital K: The recommended moisturizer.
Regenerance Active: recommended moisturizer for sensitive skin.
Mesoestetic Complete sunblock: Highly recommended for continuous use.
Melanogel Touch: this can be applied on heavy spots. Recommended for added benefit.
Melanogel Touch anti-spot cream: this depigmentation cream works very well to maintain results during stabilization period.
13
What are important instructions before using Cosmelan?
Read More
IMPORTANT NOTE: The treatment results are largely dependent on your cooperation and adherence to the post treatment skin care! The first 4 months constitute the treatment period. The period following is called the stabilisation period, and this is ideally extended up to one year, or longer. Every effort should be made to continue treatment throughout the first summer. Even if the depigmentation treatment was a great success, you need to understand that long term success depends on how well the protocol is followed, during both the treatment and stabilization phases. Avoid sun exposure for 2 weeks prior to treatment.
14
Can Cosmelan be combined with other treatments?
Read More
No peels can be done 2 weeks prior to treatment, No Laser treatment can be done on area to be treated 2 days prior to peel, Avoid Botox and Filler in area to be treated 2 weeks prior to peel.

The Cosmelan treatment is available in Johannesburg at Fourways, Parkhurst, Morningside, Bedfordview, West Rand and Illovo as well as in Pretoria at Brooklyn and Irene and in the Western Cape at Cape Quarter, Claremont, Constantia, Stellenbosch, Willowbridge, Paarl and KwaZulu-Natal at Durban & Umhlanga.

Skin ageing caused by systematic sun exposure, facial blemishes due to excessive pigmentation and, in general, imperfections caused by melanin, are more and more common problems today… “Dark blemishes”, especially on hands and face, are one of the greatest aesthetic concerns of modern men and women… It will only be possible to remove the anti-aesthetic skin blemishes and recover the smoothness of the skin, bringing back its luminosity, with a treatment that has a direct effect on the intimate formation process of the pigment (melanin).

Cosmelan Depigmentation treatment action mechanism is based on the inhibition of tyrosinase, a basic enzyme in the melanin formation process. Several of the substances present in the Cosmelan® formula act by blocking this enzyme, or even by inverting the metabolic process of the transformation chain. Melanogenesis comprises the following stages:

TYROSINE proceeds to DOPA by means of TYROSINASE.
DOPA proceeds to DOPAQUINONE by means of TYROSINASE.
DOPAQUINONE proceeds to PHAEOMELANINE and EUMELANIN by means of oxidation and cyclization.

The Cosmelan Depigmentation treatment offers a series of major advantages and benefits compared with other types of depigmentation products found in the market:

Very effective in all types of Melasma especially deep seated severe Melasma or post inflammatory hyperpigmentation PIH
Effective for pigmentation that has failed to resolve after traditional skin lightening topical products
Effective for pigmentation that has failed to resolve after traditional treatments such as superficial peels
Rapid and easy depigmenting action
Compatible with ALL skin types (Fitzpatrick I – VI)
Light peeling effect
Treatment can be used all year round
Beneficial for acne patients and the PIH after acne has resolved
Does not contain Hydroquinone or TCA
High safety margin

In 99% of the cases, the disappearance of the blemishes improves by 95%...
ONE WEEK after starting the Cosmelan® Depigmentation treatment, a noticeable significant improvement of the skin is observed! The reduction of the treated blemish is detected and the appearance of new luminous and rejuvenated skin is present.

At the end of the Cosmelan® Depigmentation treatment, the blemishes start to disappear altogether, so that, although the patient may be able to “locate” the place where the spot was, the truth is that the pigmentation will have disappeared and nobody will be able to see it just by looking at it

Cosmelan works by blocking the process that causes hyperpigmentation. It works for:

Melasma
Brown Spots
Blotchy Skin
Hyperpigmentation
Post-inflammatory hyperpigmentation of dermatitis and acne cars
Prevention of hyperpigmentation post-laser and post-peel

Cosmelan 1 – mask

Azelaic Acid, Kojic Acid, Phytic Acid, Ascorbic Acid, Arbutine, and Titanium Dioxide

Cosmelan 2 – Maintenance Cream (30g)
Titanium Dioxide, Kojic Acid, Phytic Acid, Ascorbic Acid

Mesoestetic Hydra Vital Factor K Cream (50ml)
Hydro nutritional cream for face and neck. Hydroviton, VItamin K, Vitamin E, Amniotic fluid, Glycerine, Silicone oil.

Important: it must be known if the patient has undergone any previous treatments, especially with glycolic acid. If confirmed, any treatment, especially Glycolic Acid, must be eliminated at least, one week prior to using Cosmelan Depigmentation treatment.

The Cosmelan® Depigmentation treatment initiated at the medical office must be continued at home, on a daily basis, according to the guidelines indicated.

The treatment must not be interrupted under any circumstances, during the whole time prescribed.

It is completely forbidden to combine the Cosmelan® Depigmentation treatment with other depigmentation treatments, as the appearance of undesired effects cannot be guaranteed.

Treatment control visits are recommended. 8 days after beginning of treatment, 15 days after, and a follow up visit every month thereafter.

First and second day

During the first two days of the treatment, the skin may turn red. If the skin is very sensitive, the patient may experience an itching feeling. Slight burning and tightening of the skin is also absolutely normal, especially during the first 24 to 48 hours after starting the treatment. To relieve these problems, it is advisable to apply the Mesoestetic Hydra-vital factor K whenever necessary.

Reddening of the Skin. The reddening that occurs on the face after applying the Mesoestetic Cosmelan mask treatment is similar to the effects of day-long exposure to the sun in the snow without protection. (Intense reddening in photo type I and II and practically non existent in photo type IV and V).

Flaking may occur on all skin types (and more intensely in photo types I and II) between the second and third day. In this case it is advisable to apply the Mesoestetic® Hydra-vital factor K cream, repeating this every two hours on the day when the flaking is most intense repeating this every 2 hours until it improves. Do not pull on the flakes. Do not rub or scratch the skin. If necessary flakes can be cut off. Do not use exfoliants, scrubs or peels. Avoid steam baths, saunas and swimming in a hot spring for 2 weeks following treatment. It is advisable to wait until the initial flaking period is over before starting to apply make-up again.
Warning
If a severe skin reaction results from treatment do not proceed with maintenance treatment. Similarly, if scab formation is seen or if the skin is accidentally injured during the treatment period it is advisable to interrupt application of maintenance treatment. Use only Hydra-vital factor K and Sunscreen until the skin has settled and then again proceed with the maintenance treatment schedule. If in doubt, please contact your doctor at Skin Renewal immediately.

Third and fourth day. After the third or fourth day, the skin appears healthy and luminous and the marks begin to fade.

HOME TREATMENT – Cosmelan Maintenance Cream

The second phase of the Cosmelan consists of a home maintenance cream Cosmelan with the intention of securing the depigmentation by association of agents such as Kojic Acid, Phytic Acid, and Vitamin C. We have added a physical agent to block the sun and guarantee that the UV rays do not keep on aggravating unwanted cutaneous hyper pigmentation.

The period following the initial 6 month treatment process, is called the STABILISATION period, and this can ideally be extended up to one year. Every effort should be made to continue treatment throughout the first summer. Even if the treatment is a great success, long term success depends on how well the protocol is followed, during both the treatment and stabilization phases. VERY GOOD sunblock is essential at all times.

Mesoestetic Vitamin C ampoules: use twice weekly before applying the Cosmelan 2 cream.

Hydra Vital K: The recommended moisturizer.

Regenerance Active: recommended moisturizer for sensitive skin.

Mesoestetic Complete sunblock: Highly recommended for continuous use.

Melanogel Touch: this can be applied on heavy spots. Recommended for added benefit.

Melanogel Touch anti-spot cream: this depigmentation cream works very well to maintain results during stabilization period.

IMPORTANT NOTE: The treatment results are largely dependent on your cooperation and adherence to the post treatment skin care! The first 4 months constitute the treatment period. The period following is called the stabilisation period, and this is ideally extended up to one year, or longer. Every effort should be made to continue treatment throughout the first summer. Even if the depigmentation treatment was a great success, you need to understand that long term success depends on how well the protocol is followed, during both the treatment and stabilization phases. Avoid sun exposure for 2 weeks prior to treatment.

No peels can be done 2 weeks prior to treatment, No Laser treatment can be done on area to be treated 2 days prior to peel, Avoid Botox and Filler in area to be treated 2 weeks prior to peel.

*Please note results may vary by individuals.

Review -"Face Pigmentation"

Reviewed on 7 July 2018 by Lulu Khumalo

Skin Renewal Bedfordview

Cosmelan Depigmentation

But surprisingly the staff was excellent. Starting from the reception to the Dr. Will recommend Bedfrodview to everyone.

Well it was my first time to come and know more about my pigmentation on my face. I was so scared that maybe they will say there is nothing that they can do

because I have been like this for a very long time. But surprisingly the staff was excellent. Starting from the reception to the Dr. Will recommend Bedfrodview to everyone.

Review -"I have been coming here for years!"

Reviewed on 26 November 2015 by Chauke

Skin Renewal Parkhurst

Cosmelan Depigmentation

I have been coming here for years now and been with Kelly throughout. I am very pleased with her work and have been seeing great results as well. She is professional as well as really relaxed, calm and makes the experience really special all the time.

Review -"Consistent Professional Excellence!"

Reviewed on 26 October 2015 by Sorina Oberholzer

Skin Renewal Cape Quarter

Cosmelan Depigmentation

Melissa is highly personable and extremely professional. I trust her skill and recommendations implicitly and I am comfortable around her (she also happen to be one of my favourite people all round). She delivers consistently high treatment standards!

Review -"Cosmelan is amazing!"

Reviewed on 17 August 2015 by K.M from Cape Quarter

Skin Renewal Cape Quarter

Cosmelan Depigmentation

The Cosmelan treatment is the best thing that ever happened to my skin. Pigmentation is almost gone, my skin texture is amazing and my skin looks radiant. My skin therapist was amazing, she followed up with me and answered all my questions. Cosmelan is amazing!

Cosmelan Depigmentation

Cosmelan Depigmentation at a Glance

Frequently Asked Questions

4 Reviews (average: 5 out of 5)