Neoretin is a daily skin brightening regimen for melasma, dark spots and uneven pigmentation. Ingredients in the Brightening Booster System act to inhibit all stages of melanin production, whilst the new RetinSphere retinoid technology offers the efficacy of retinoids without the side effects. Neoretin is suitable for skin which does not tolerate hydroquinone (HQ), or when HQ use is discontinued.