Pioneered by the French physician Dr. Michel Pistor in 1952, Mesotherapy is a minimally invasive procedure that is widely used in Europe and elsewhere to treat various injuries and medical conditions. Tiny "medicinal bullets" are delivered directly into the mesoderm (middle layer of skin) by micro injections that are highly specific to the condition being treated. By definition any medication injected into the skin, fat or tissues of Mesoderm (middle layer of skin) is considered Mesotherapy. Mesotherapy is also known as Lipodissolve/Injection Lipolysis.

The outcome of any Mesotherapy procedure is directly dependent on what active ingredients are used and what problems it addresses:

At Skin Renewal for anti ageing benefits we use a Dermaheal Skin Rejuvenation Solution SRS which thoroughly re-hydrates and plumps out the dermis as it contains:

• Recombinant human growth factors; Epidermal Growth Factor (EGF), basis Fibroblast Growth Factor (bFGF), Insulin Growth Factor-1 (IGF-1);
• Dermaheal Skin Rejuvenation Solution SRS also contains peptides; Thioredoxin (TRX) and Copper Peptide and
• 55 additional supporting ingredients; 4 x Coenzymes, 15 x Vitamins, 24 x Amino Acids, 4 x Minerals, 4 x Nucleic Acids and 2 x Reducing agents (antioxidants);
• Retinol, Ascorbic acid and Glutathione - powerful antioxidants and direct stimulators of collagen remodeling and pigmentation reducing agents.

At Skin Renewal for anti ageing and rehydration benefits we use a Dermaheal Skin Rejuvenation Solution SRS with Hyaluronic Acid which thoroughly

re-hydrates and plumps out the dermis as it contains:

• Recombinant human growth factors; Epidermal Growth Factor (EGF), basis Fibroblast Growth Factor (bFGF), Insulin Growth Factor-1 (IGF-1);
• Dermaheal Skin Rejuvenation Solution SRS also contains peptides; Thioredoxin (TRX) and Copper Peptide and
• 55 additional supporting ingredients; 4 x Coenzymes, 15 x Vitamins, 24 x Amino Acids, 4 x Minerals, 4 x Nucleic Acids and 2 x Reducing agents (antioxidants);
• Retinol, Ascorbic acid and Glutathione - powerful antioxidants and direct stimulators of collagen remodeling and pigmentation reducing agents
• And Hyaluronic acid which attracts water and instantly plumps out the dermis.

At Skin Renewal for pigmentation problems we use Dermaheal Skin brightening serum which addresses, pigmentation on multiple fronts as it is enriched with the newest biotechnology for pigmentation problems, namely

• pentapeptide 13 and
• TGP protein complexes.
• Brightening serum utilizes a dual melanin inhibition mechanism; Inhibits tyrosinase activity to prevent melanin production;
• Blocks melanocyte activation before the tyrosinase is even produced;
• Synergistic double peptide complex combination;
• While the pigmentation component of the serum takes care of pigment, the peptides still stimulate cellular regeneration and differentiation.

At Skin Renewal for reduction of double chins and facial sculpting: we use Dermaheal lipolytic which contains

• PPC (phosphatidylcholine) which destroys fat cell
• Growth factors for collagen stimulation

The mesotherapy is introduced into the skin either by small micro injections or by transdermal mesotherapy in patients who have a fear of needles (see Transdermal Mesotherapy) The needles used in Mesotherapy are very short and thin so the doctor can deliver the medications to the right depth.

Different mesotherapy ingredients are used for different indications. In addition, the long term results of Mesotherapy treatments are very dependent on what active ingredients are present in the Mesotherapy solution and how many treatments are prescribed.

At Skin Renewal for anti ageing benefits we use a combination of award winning growth factors , peptides, amino acids, vitamins, nucleic acids, co factors and hyaluronic acid.( see above)

These combinations present in the cocktail stimulate the production of collagen so that the dermis is strengthened thereby improving skin tone and texture . The hyaluronic acid present in the cocktail attracts water and rehydrates the skin resulting in an improved appearance. For pigmentation, patented pigmentation inhibiting peptides are used to improve hormonal pigmentation.

At Skin Renewal we use Mesotherapy to treat the following:

• Mesotherapy for Anti Ageing benefits.
• Mesotherapy for Anti Ageing benefits and rehydration of the skin
• Mesotherapy for pigmentation problems especially hormonal pigmentation and also for skin brightening.
• Mesotherapy for reduction of double chins and facial sculpting

On the Face for facial sculpting Mesotherapy treats:

• Double chin
• Fat or Flabby cheeks
• Fatty Eye Bags
• Facial sculpturing
• Skin Rejuvenation

Skin Renewal anti ageing facial combinations includes Mesotherapy with medical strength problem specific active ingredients to ensure superior results for following:

• Anti Ageing
• Firming
• Hydrating
• Hormonal Pigmentation
• Sensitive Skin

For Anti Ageing skin rejuvenation: Intrinsic ageing, also known as the natural ageing process, is a continuous process that normally begins in our mid-20s. Within the skin, collagen production slows, and elastin, the substance that enables skin to snap back into place, has a bit less spring. Dead skin cells do not shed as quickly and turnover of new skin cells may decrease slightly. While these changes usually begin in our 20s, the signs of intrinsic ageing are typically not visible for decades.

For anti ageing benefits, mesotherapy with Growth Factors stimulates the fibroblasts to produce collagen, which is the major support structure for the skin. If one can keep one's skin firm and taught with collagen, then the sagging that takes place over time can be contained as tighter skin supports the soft tissues of the face and body.

A series of treatments is necessary usually 1 treatment every 10 days foe the first month and then 1 treatment every 6 to 12 weeks for maintenance. Rather than waiting until their problems are bothersome again, patients must appreciate that maintenance goes a long way and that single mesotherapy treatments should be repeated twice yearly after an initial course.

For anti ageing benefits, our signature Treatment 3 D Skin Rejuvenation™ combines mesotherapy safely and effectively with laser and light treatments

The safety of the procedure is dependent on who injects the Mesotherapy product and how it is injected. At Skin Renewal, mesotherapy / Lipodissolve treatments are only performed by doctors and strict aseptic condition adhered to. Hundreds of treatments have been administered to our patients with great results and minimal downtime and side effects

Mesotherapy was recognized by the French National Academy of Medicine in 1986 as an integral part of traditional medicine. Each day, thousands of doctors worldwide use Mesotherapy to help tens of thousands of patients.

For anti ageing mesotherapy there is no downtime at all especially if Transdermal (no needle) mesotherapy is used .After mesotherapy for double chin and fat reduction, (Lipodissolve) , a mild redness and swelling of the skin occurs following the procedure which usually resolves within 1 to 3 days However, since the introduction of a radiofrequency RF procedure after the Mesotherapy treatment especially for the double chin, there are only mild side effects such as swelling and bruising which resolve without any consequences and we have seen a dramatic improvement in long term results see RAIL-THIN.

For best results for a double chin reduction, 4 to 8 treatments are needed 2 weeks apart.

Mesotherapy safely treats all skin types without significant pain or down-time. It can erase centimeters of the areas treated in 4 to 6 treatment sessions one week apart.

Mesotherapy Treatments are available in Johannesburg, Sandton, Pretoria and Cape Town at the Rivonia, Parkhurst, Sandton, Fourways, Irene, Cape Quarter, Claremont, Stellenbosch and Willowbridge branches

Skin Renewal Tip:

Unfortunately a "a perfect skin" has not been handed out by nature - it has to be bought and this usually comes at an expensive price. At Skin Renewal we have recognized this problem and have come up with a solution to make 3 D Skin Rejuvenation ™ affordable for most people. After consultation with the aesthetic doctor, a package with a customized solution according to your needs will be recommended. As best results are usually seen after 6 to 12 treatments every client is provided with a year long solution dependant on budget and expectations. Each treatment has prolonged effects thus a monthly treatment can be given over a period of time until the desired result is achieved. The effect of each treatment is accumulative with best results down the line.

A Liquid Facelift to replace volume loss that occurs with age is recommended to complement the 3D Laser Lift procedure.